Pills travel through the gut and the liver before reaching circulation. The result is slower onset, lower availability, and dosing that drifts with meals, microbiome, and metabolism. Topicals sit on the skin and rarely cross it. Injections cross it well — but ask you to handle a needle.1
"We set out to investigate a wearable that delivers active compounds through the skin — controlled, on demand, without needles and without the first-pass loss."
Melve™ Smart Patch is a research device built on three principles: a two-part architecture that keeps electronics out of the waste stream; an active iontophoretic driver that moves target molecules across the skin at safe current densities; and a Bluetooth link to a phone app that lets you pick the curve — ramped, pulsed, or continuous.2
The outcome: faster onset, higher availability, more consistent dosing — in a format that is quiet, hygienic, and worn like nothing else you wear.
